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Searched Htb for 失效***, found 1,
sit'hau [wt] [HTB] [wiki] [[...]] 
lose legal; be invalidated; null and void; (medicines) lose potency or efficacy (usually because of a prolonged lapse of timeD4358)
失效

DFT
🗣 sit'hau 🗣 (u: sid'hau) 失效 [wt][mo] sit-hāu [#]
1. () (CE) to fail; to lose effectiveness || 失效
tonggi: ; s'tuix:

Maryknoll
sit'hau [wt] [HTB] [wiki] u: sid'hau [[...]][i#] [p.]
lose legal, be invalidated, null and void, (medicines) lose potency or efficacy (usually because of a prolonged lapse of timeD4358)
失效